Omega-3 and Ubiquinol (active CoQ10)  have complementary nutritional roles as part of a heart-healthy lifestyle.​​

💡 TAKING A STATIN?​

Statins work by reducing cholesterol production through the mevalonate pathway, which is also reduce the production of CoQ10.​

Studies have found that statin therapy can reduce blood CoQ10 levels by roughly 50% after 30 days treatment.​

For statin users, Ubiquinol (active CoQ10) supplementation may be worth discussing with your doctor or pharmacist.​

Types of CoQ10​

• CoQ10 exists in two interconvertible forms within the body. ​
• Healthy individuals convert between both forms naturally.​

The Roles of Ubiquinol & Omega-3 in Heart Health

⚡UBIQUINOL— POWER​

Energy + Antioxidant Defence​

• Supports mitochondrial adenosine triphosphate (ATP) production to meet the heart’s high energy demands​
• Provides antioxidant defence​
• Helps protect LDL-cholesterol from oxidation​
• Deficiencies is associated with Cardiovascular disease (CVD)​

🛡️ OMEGA-3 — PROTECT​

Lipid + Cardiovascular Support​

• Helps lower the risk for CVD by improving key heart health markers like blood lipids and blood pressure​
• Helps lower triglyceride (TG) levels​
• Supports healthy HDL-cholesterol levels​
• Supports healthy blood vessel function & flexibility​
• Supports normal heart rhythm​
• Regulate the level of inflammation​

WHY COMBINE THEM?​

THE QUALITY HEART DUO in POWER & PROTECT​

• Omega-3 and Ubiquinol provide complementary nutritional support as part of a heart-healthy lifestyle.​

References

1. Zozina, V. I., Kondratenko, S. N., Shikh, E. V., Krasnykh, L. M., Melnikov, E. S., & Kukes, V. G. (2023). The Influence of Atorvastatin, Amlodipine and Ethoxidol on Ubiquinol and Ubiquinone Endogenous Plasma Concentrations in Patients with Chronic Heart Failure. Current drug metabolism, 24(9), 635–644. https://doi.org/10.2174/1389200224666230913133201 ​
2. Langsjoen, P. H., & Langsjoen, A. M. (2014). Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clinical pharmacology in drug development, 3(1), 13–17. https://doi.org/10.1002/cpdd.73 ​
3. Mei, X., Zhu, B., Soni, K., Kasaraneni, K., & Panchal, N. (2026). A Randomized, Double-Blind, Two-Treatment, Two-Period, Crossover Study Investigating the Systemic Bioavailability of a Novel Cocrystal Ubiquinol Formulation Compared with a Ubiquinone Formulation in Healthy Adults. Clinical pharmacology in drug development, 15(3), e70042. https://doi.org/10.1002/cpdd.70042 ​
4. Sabbatinelli, J., Orlando, P., Galeazzi, R., Silvestri, S., Cirilli, I., Marcheggiani, F., Dludla, P. V., Giuliani, A., Bonfigli, A. R., Mazzanti, L., Olivieri, F., Antonicelli, R., & Tiano, L. (2020). Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial. Nutrients, 12(4), 1098. https://doi.org/10.3390/nu12041098 ​
5. Saini R. (2011). Coenzyme Q10: The essential nutrient. Journal of pharmacy & bioallied sciences, 3(3), 466–467. https://doi.org/10.4103/0975-7406.84471 ​
6. Bernasconi, A. A., Wiest, M. M., Lavie, C. J., Milani, R. V., & Laukkanen, J. A. (2021). Effect of Omega-3 Dosage on Cardiovascular Outcomes: An Updated Meta-Analysis and Meta-Regression of Interventional Trials. Mayo Clinic proceedings, 96(2), 304–313. https://doi.org/10.1016/j.mayocp.2020.08.034
7. Marcoff, L., & Thompson, P. D. (2007). The role of coenzyme Q10 in statin-associated myopathy: a systematic review. Journal of the American College of Cardiology, 49(23), 2231–2237. https://doi.org/10.1016/j.jacc.2007.02.04